A more pronounced wound contraction and granulation tissue formation has been observed with Sinusoidal Pressure Therapy
Sinusoidal therapy is an interesting alternative that ensures smooth transitions between 2 different levels of negative pressure and thus relieve patient pain, while retaining the acceleration in healing.10
A highly prominent Leukocyte infiltration and tissue disorganization has been observed.
Sinusoidal therapy have more profound beneficial effects on the blood flow around the wound edges, including an increase in blood flow 2.5 cm from the wound edge, known to facilitate oxygenation and nutrient supply, accompanied by a decrease in blood flow close to the wound edge (0.5 cm), known to stimulate angiogenesis and granulation tissue formation.
Wound contraction during continuous negative pressure wound therapy (NPWT), intermittent pressure therapy(IPT), and variable pressure therapy (VPT) using gauze or foam.