Search by Blog
Read by Category

Your healing journey continues beyond this blog

Find the right products for better recovery at online store
Cart Image
US Patent Granted For An Artificial Skin Substitute

Patent No.1: US 10, 004, 830 B2
Date of the Patent Granted: Jun. 26, 2018
Patent No.3: US 10, 149, 924 B1
Date of the Patent Granted: Dec. 11, 2018
Patent No.2: US 10, 098, 986 B1
Date of the Patent Granted: Oct. 16, 2018
Title of the Patent: READY TO USE BIODEGRADABLE AND BIOCOMPATIBLE ARTIFICIAL SKIN SUBSTITUTE AND A METHOD OF PREPARATION THEREOF

NEED OF THE INVENTION:

Wound Healing is a complex biological process. The main goal of the treatments is to achieve wound closure. In the cases of large wounds like burns, the availability of skin covers to repair the damaged areas is a problem. Different treatment modalities are available depending upon the type of the wound and the physician’s approach.

These may include surgical closure (primary intention), wound left open to close by a reparative process (secondary intention) or wound left open because of infection and closed surgically later (tertiary intention).

Since the primary goal is wound closure, the quality of healing is important because in the cases of deeper wounds the chances of infection and scar formation are very high.

Mesenchymal stem cells are progenitor cells of mesoderm origin. These were initially isolated from bone marrow. However, at present these can be isolated from the number of tissue niches including dental pulp, adipose tissue, umbilical cord, umbilical cord blood, skin, skeletal muscle etc. These are multipotent, immune-privileged cells, which can differentiate into multiple lineages including skin cells.

Therefore, they have been very instrumental in the field of regenerative medicine. Skin is the largest organ of the body and harbors stem cells within it which helps in repair. However, in the case of chronic wounds, the normal repair process gets delayed and it takes the very long time to heal.

This can be the result of various disorders like diabetic foot ulcer, severe burns, vasculitis etc. Chronic wounds cause substantial patient morbidity, with detrimental effects on patient quality of life, increasing pain, stress, depression, and social isolation.

Normal wound healing occurs in 3 stages:
1) Inflammation
2) Proliferation
3) Remodeling.

We @ Datt Mediproducts have developed a stem cell-based extracellular matrix for the treatment of burns, diabetic foot ulcer, and other chronic wounds. This matrix has tissue-like properties and can be used for wound healing. This patent describes the invention as well as the in-vitro method of cell-based skin substitute preparation.

ABOUT THE INVENTION:

The present invention provides a novel and unique technique of culturing of proliferating human mesenchymal stem cells on a biocompatible matrix membrane to form a confluent layer of cell sheet with secreted growth factors, suitable for grafting. This invention also provides a ready to use biodegradable and biocompatible tissue construct with autologous/allogeneic human stem cell-based product.

The innovative product has tissue-like properties and is a very effective, easy to use, cost-effective artificial skin substitute. The present invention uses proliferative/confluent Mesenchymal stem cells (MSCs), fibroblast, keratinocytes, and Mesenchymal stem cells differentiated fibroblast and keratinocytes whereby cells are transferred from culture to the wound bed.

This product not only helps to achieve satisfactory wound closure but also helps to restore functional integrity in the least time and with the least complications and morbidity.

Advantages of the Invention:
– Provides the support, growth factors and essential cytokines for wound healing.
– The scaffold of the present invention does not stick to the wound.
– The present invention comprises of improved wound and hygiene.
– It can be manufactured in any size and shape as per the requirement.
– Easy to handle.
– It can be removed easily.
– Environment friendly as it is degradable easily.
– It aids in wound healing.
– It ensures rapid healing of wound.
– It ensures moist wound environment by preventing wound desiccation.

The graft can be made within 15 days. It is an alternative treatment to the standard wound management therapies. There is a dramatically reduced risk of transmission of infectious disease due to rigorous process controls.

INTENDED USE:

Grafting to a patient with tissue or organ defect, such as skin ulcer or wound, or in vitro tissue testing or animal graftings such as for safety testing or validation of pharmaceutical, cosmetic, and chemical products.

Follow us @ Datt Mediproducts to know more about the company and product.

Visit www.dattmedi.com for more infomation.
Share:
Recent Blogs
Wound during physical activity

Recovery doesn’t mean slowing down. Staying active while recovering from an injury or managing a wound doesn’t have to be an impossible task. With the right products and strategies, you can keep moving while ensuring that your recovery stays on track.

Whether you’re returning to your workout routine after surgery, dealing with an orthopedic injury, or healing a wound, we’ve got you covered.  Let’s dive into how you can integrate orthopedic and wound care products into your active lifestyle to keep you on the move and in the game.

The hidden risks of being active during recovery

Exercise helps circulation and mental health, but certain movements can disrupt healing. 
For wounds, bending, twisting, or sweating can weaken dressings and delay recovery.

EXAMPLE

Imagine a wound that’s healing well, but every time you move, the bandage loosens or moisture from sweat causes irritation. That can delay healing, reopen a wound, or even introduce bacteria. Similarly, orthopedic injuries like fractures or sprains require careful management to avoid strain that hinders healing.

The first rule of staying active during recovery?

Keep wounds protected during physical activity. The right products will shield your injury from friction, dirt, and moisture while allowing the skin to breathe. Opt for dressings that stay secure, comfortable, and irritation-free.

Our top products for Active Healing

When it comes to active recovery, we understand that you need products that work with you, not against you. That’s why we recommend products designed for ultimate support and flexibility.

  • Velpore™, Pressure-Sensitive Adhesive Tape:
    Hypoallergenic and breathable, it keeps dressings in place during physical activity without skin irritation.
  • Velfix® T+Pad, Waterproof Dressing:
    Ideal for post-surgical recovery, this waterproof dressing provides a bacterial barrier while you stay active.
  • Velfix® -T Film, Transparent Dressing:
    Clear, waterproof, and flexible, it offers protection while maintaining full range of motion.

When dealing with an orthopedic injury, immobilization is essential—but that doesn’t mean you have to sit on the sidelines.  Whether it’s a sprain, strain, or fracture, finding the right orthopedic product can help ensure that your recovery stays on track, even as you navigate through your day-to-day activities.

Hygiene: Clean up after movement

Excess sweat and dirt can compromise wound care. Velfix® -T+Pad helps manage moisture and ensures easy post-workout cleaning, preventing infection while maintaining healing.

While staying active is crucial, some exercises may be more beneficial than others during recovery. Low-impact activities like walking, swimming, or cycling can promote healing without overstraining your injury.

Recognize when to pause

Pay attention to swelling, redness, or increased pain after activity. If these occur, rest and assess—early intervention ensures faster recovery.

Holistic Healing: Rest & Nutrition

Healing requires proper rest and nutrition. A balanced diet, hydration, and enough sleep support tissue repair and overall recovery. Include vitamins, protein, and antioxidants to aid healing. Stay active and heal efficiently by using the right wound care and orthopedic products. With proper protection, hygiene, and mindful activity, your recovery journey can stay on track.

Choosing the Right Compression Stocking for Varicose Veins

Varicose Veins are enlarged, twisted veins that bulge under your skin. They normally develop when blood flow is obstructed and are more than just a cosmetic concern; they can cause discomfort and, if untreated, lead to more serious health issues. Medical compression stockings and wraps, such as the Velcare® range from us, provide an effective solution for managing varicose veins. Understanding their benefits and features can help you make an informed choice.

Velcare® -Varicose Veins Stocking: Support Where You Need It

Designed to offer Class 2 Compression (23-32mmHg), Velcare® -Varicose Veins Stocking are ideal for promoting circulation and reducing varicose vein symptoms. The graduated compression applies gentle pressure from the ankle upwards, aiding blood flow back to the heart.

Key Features of Velcare® -Varicose Veins Stocking:

  • Effective Compression: Reduces swelling and discomfort associated with varicose veins.
  • Comfortable Wear: Soft, breathable, latex-free materials ensure all-day comfort.
  • Durable Construction: Four-way stretchability enhances flexibility and durability for long-term use.
  • Medical Grade Quality: Designed to meet medical standards for effective varicose vein management.


Velcare® -Inelastic Wrap: Customizable Compression

For those preferring an alternative to traditional stockings, Velcare® -Inelastic Wrap provides targeted calf compression without constant adjustment. Adjustable straps offer a customized fit for optimal compression therapy tailored to individual needs.

Key Features of Velcare® -Inelastic Wrap:

  • Targeted Compression: Focuses on calf muscles for effective circulation support.
  • Adjustable Fit: Velcro straps ensure a secure fit and ease of adjustment.
  • Ease of Use: Simple application and removal for convenient daily wear.
  • Breathable Material: Allows the skin to breathe, suitable for extended use.

Choosing the Right Option for You

When deciding between Velcare® -Varicose Veins Stocking and Velcare® -Inelastic Wrap, consider your lifestyle, comfort preferences, and specific medical needs. Both options offer effective relief for varicose veins, with the stockings providing graduated compression and the wrap offering targeted support and ease of use.

Whether you choose the graduated compression of Velcare® -Varicose Veins Stocking or the targeted support of Velcare® -Inelastic Wrap, we as Datt Mediproducts, ensures you receive high-quality products designed to improve circulation and alleviate varicose vein symptoms. Explore more about Velcare® products and find the right solution for managing your varicose veins with us.

×