US Patents Granted – Datt Mediproducts Pvt Ltd

“A patent is an intellectual property right which provides it’s owner right to exclude others from making, using, selling, and importing an invention for a limited period of time, usually twenty years, without authorization.”

The Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement between the member nations of the World Trade Organization (WTO) specifies the protection and enforcement procedures for all the intellectual property rights including Patents.

We @ Datt Mediproducts (DMP), are devoted to manufacturing & marketing of products of impeccable quality conforming to international standards. The Department of Life Sciences (DLS) is a research and development wing of Datt Mediproducts, recognized by the Department of Scientific and Industrial Research (DSIR), a unit of Government of India, with the state-of-the-art facility and well qualified and committed scientific staff working on the development of advanced wound care management.

DMP applied for 17 patents worldwide. Read further to know more about the patents which have been granted in the US.

US Patent No.: US 10,124,084 B2
Date of the Patent Granted: Nov. 13, 2018
Title of the Patent: A READY TO USE BIODEGRADABLE AND BIOCOMPATIBLE DEVICE AND A METHOD OF PREPARATION THEREOF

Brand: VELSEAL
The patent is granted for both the product as well as the process of its manufacturing. The invention is a ready to use the biodegradable and biocompatible device with high porosity, used to stop bleeding within a couple of minutes. The scaffold of the present invention comprises of a combined application of air dry and freeze dry method. The invention has excellent ventilation properties and can easily be removed from the wound without causing any extra hemorrhage.


US Patent No.:
US 10,076,552 B2
Date of the Patent Granted: Sep. 18, 2018
Title of the Patent: MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION / MANUFACTURING THEREOF

Brand: VELVERT
The second patent is for a multifunctional formulation made from natural ingredients and the process to manufacture the same. This pharmaceutical preparation consists of the water-solubilized nano-sized formulation of a non-aqueous solvent extract of phytopharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. This device is useful for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals. It also relates to the anti-cancer transdermal patch for melanoma therapy and for the treatment of Alzheimer’s and multiple sclerosis also.


US Patent No.:
US 10,004,830 B2
Date of the Patent Granted: Jun. 26, 2018
&
US Patent No.: US 10,098,986 B1
Date of the Patent Granted: Oct. 16, 2018
&
US Patent No.: US 10,149,924 B1
Date of the Patent Granted: Dec. 1, 2018
Title of the Patent: READY TO USE BIODEGRADABLE AND BIOCOMPATIBLE ARTIFICIAL SKIN SUBSTITUTE AND A METHOD OF PREPARATION THEREOF

Brand: VELGRAFT
The third invention is for the brand VELGRAFT for which three US patents have been granted. It relates to a three-dimensional cell culture system which can be used to culture a variety of different cells (Human mesenchymal stem cells, Human fibroblast, Keratinocytes, fibroblast differentiated from mesenchymal stem cells in vitro and keratinocytes differentiated from mesenchymal stem cells in vitro) in vitro for continued periods of time.

This describes an invention in which mesenchymal stem cells (MSCs) derived  are inoculated and grown on a pre-established scaffold or matrix made up of chitosan and gelatin. The developed tissue constructs contain cells, growth factors, cytokines and other regulatory factors secreted by cells and provide the support, growth factors and essential cytokines for wound healing.

This invention is useful in the treatment of non-infected burn wounds, diabetic foot ulcers, venous leg ulcers and other types of chronic skin wounds. It’s helpful in the healing and regeneration of skin tissue.

 US Patent No.: US 15/081,202
Date of Patent Granted: January 2019
Title of the Patent: Ready to Use, Hydrophilic, Self-dispersive, Fragmentable, and Biodegradable Porous Sponge Matrix and a Method of Manufacturing Thereof

Brand: VELNEZ
The 6th patent is for the invention related to a porous absorbent Composite Material, which may be used e.g. in the form of a plug or tampon, for instance for packing antrum or other cavities of the body. As it is a hydrophilic Self-Dispersive, fragmentable and Bio-Absorbable Porous Composite foam it is helpful in controlling bleeding, wound closure, prevents tissue adhesion and/or support tissue regeneration.

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Wound Care in Diabetes

Diabetes significantly increases the risk of developing chronic wounds, particularly foot ulcers. Effective wound care is crucial for preventing complications and promoting healing in diabetic patients. In this blog, you will explore the nature of diabetic wounds, prevention techniques, and management strategies to help healthcare professionals and patients navigate these challenges.

Understanding Diabetic Wounds

Diabetic wounds, especially foot ulcers, are common complications resulting from prolonged high blood sugar levels. These wounds often develop due to neuropathy (nerve damage) and peripheral arterial disease, which impair sensation and blood flow. Consequently, minor injuries can go unnoticed and progress into serious ulcers. Left untreated, these ulcers can lead to severe infections and, in extreme cases, amputations.

1. Prevention Techniques for Diabetic Ulcers:
Preventing diabetic ulcers is essential to reduce the risk of severe complications. Here are some effective prevention strategies.

2. Regular Foot Inspections: 
Diabetic patients should inspect their feet (or have someone inspect it) on a daily basis for cuts, blisters, redness, or swelling. Early detection of potential issues can prevent minor problems from becoming serious ulcers.

3. Proper Footwear: 
3a. Wearing well-fitting shoes and socks designed for diabetics can prevent pressure points and reduce the risk of injuries. 
3b. Avoid wearing tight stockings or socks with elastic tops as they can reduce blood flow.
3c. Avoid extreme hot or cold temperatures.
3d. Do not treat corn or calluses on your own. 
3e. Avoiding barefoot walking, even at home, is crucial.

4. Good Hygiene: 
Keeping feet clean and dry is essential. Patients should wash their feet daily with mild soap and water, then dry them thoroughly, especially between the toes.

5. Blood Sugar Control: 
Maintaining optimal blood sugar levels through diet, exercise, and medication can significantly reduce the risk of neuropathy and poor circulation, which contribute to ulcer formation.

6. Regular Medical Foot Check-Ups: 
Routine visits to a healthcare provider or a podiatrist for foot exams can help identify and address problems early.

Management Strategies for Diabetic Patients

When ulcers do occur, effective management is vital to promote healing and prevent complications.

Here are some key strategies:

1. Wound Cleaning and Dressing:
Keeping the ulcer clean and protected is essential. Cleaning the wound with a saline solution and using appropriate dressings, such as those provided by DMP Velvert®, can create an optimal healing environment. It provides a barrier to external contaminants, aids absorption of exudates and accelerates wound healing.

2. Debridement:
Removing dead tissue from the wound (debridement) can accelerate the healing process. This procedure should be performed by a healthcare professional.

3. Pressure Offloading:
Reducing pressure on the affected area is crucial. Patients may need special footwear, casts, or braces to alleviate pressure on the ulcer. Foot or mobility exercises also help in decreasing peak pressure, increasing foot and ankle range of motion and it improves neuropathy symptoms.

4. Infection Control:
Monitoring for signs of infection and using antibiotics when necessary is critical. Proper wound care products, like Velvert®, which offer antimicrobial properties, can help prevent infections.

5. Blood Flow Improvement:
Enhancing blood circulation through medical treatments or lifestyle changes can aid in the healing process. This might include medications, physical therapy, or surgical interventions. Revascularization results in increased tissue perfusion, which can further reduce amputation rates.

Diabetic ulcers are a serious complication of diabetes, but with proper prevention and management strategies, their impact can be significantly reduced. Regular foot inspections, good hygiene, appropriate footwear, and effective blood sugar control are key preventive measures. When ulcers do develop, it is best to catch them in the early stages when they are small, products combined with professional medical care, can promote healing and prevent complications.

At Datt Mediproducts, we offer Velvert®, an advanced wound care solution designed to aid in the management of diabetic ulcers. Velvert® dressings are crafted to provide superior moisture retention and protection, creating an optimal environment for wound healing. They also incorporate antimicrobial properties to reduce the risk of infection, which is crucial for diabetic patients.

Velvert® is easy to apply and remove, ensuring minimal discomfort for patients. For those seeking reliable and high-quality wound care products, visit and explore at https://dattmedi.com/velvert.html.

Visit www.dattmedi.com to learn more about our high-quality wound care solutions designed to support diabetic patients.

Preventing Catheter Related Blood Stream Infections With VELVERT DISC

Healthcare-associated infections (HAIs) are one of the most prevailing adverse events among hospitalized patients. These nosocomial infections are a leading cause of morbidity and mortality among critically ill hospitalized patients, especially in intensive care units (ICUs).

The most serious among these infections develop at the vascular access sites and are called as the Central Venous Catheter-associated Bloodstream Infections (CVC-BSIs) or may also be labeled as the Catheter-Related Blood Stream Infections (CRBSI).

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