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US Patents Granted – Datt Mediproducts Pvt. Ltd.

“A patent is an intellectual property right which provides it’s owner right to exclude others from making, using, selling, and importing an invention for a limited period of time, usually twenty years, without authorization.”

The Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement between the member nations of the World Trade Organization (WTO) specifies the protection and enforcement procedures for all the intellectual property rights including Patents.

We @ Datt Mediproducts (DMP), are devoted to manufacturing & marketing of products of impeccable quality conforming to international standards. The Department of Life Sciences (DLS) is a research and development wing of Datt Mediproducts, recognized by the Department of Scientific and Industrial Research (DSIR), a unit of Government of India, with the state-of-the-art facility and well qualified and committed scientific staff working on the development of advanced wound care management.

DMP applied for 17 patents worldwide. Read further to know more about the patents which have been granted in the US.

US Patent No.: US 10,124,084 B2
Date of the Patent Granted: Nov. 13, 2018
Title of the Patent: A READY TO USE BIODEGRADABLE AND BIOCOMPATIBLE DEVICE AND A METHOD OF PREPARATION THEREOF

Brand: VELSEAL
The patent is granted for both the product as well as the process of its manufacturing. The invention is a ready to use the biodegradable and biocompatible device with high porosity, used to stop bleeding within a couple of minutes. The scaffold of the present invention comprises of a combined application of air dry and freeze dry method. The invention has excellent ventilation properties and can easily be removed from the wound without causing any extra hemorrhage.

US Patent No.:US 10,076,552 B2
Date of the Patent Granted: Sep. 18, 2018
Title of the Patent: MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION / MANUFACTURING THEREOF

Brand: VELVERT
The second patent is for a multifunctional formulation made from natural ingredients and the process to manufacture the same. This pharmaceutical preparation consists of the water-solubilized nano-sized formulation of a non-aqueous solvent extract of phytopharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. This device is useful for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals. It also relates to the anti-cancer transdermal patch for melanoma therapy and for the treatment of Alzheimer’s and multiple sclerosis also.

US Patent No.:US 10,004,830 B2
Date of the Patent Granted: Jun. 26, 2018
&
US Patent No.: US 10,098,986 B1
Date of the Patent Granted: Oct. 16, 2018
&
US Patent No.: US 10,149,924 B1
Date of the Patent Granted: Dec. 1, 2018
Title of the Patent: READY TO USE BIODEGRADABLE AND BIOCOMPATIBLE ARTIFICIAL SKIN SUBSTITUTE AND A METHOD OF PREPARATION THEREOF

Brand: VELGRAFT
The third invention is for the brand VELGRAFT for which three US patents have been granted. It relates to a three-dimensional cell culture system which can be used to culture a variety of different cells (Human mesenchymal stem cells, Human fibroblast, Keratinocytes, fibroblast differentiated from mesenchymal stem cells in vitro and keratinocytes differentiated from mesenchymal stem cells in vitro) in vitro for continued periods of time.

This describes an invention in which mesenchymal stem cells (MSCs) derived are inoculated and grown on a pre-established scaffold or matrix made up of chitosan and gelatin. The developed tissue constructs contain cells, growth factors, cytokines and other regulatory factors secreted by cells and provide the support, growth factors and essential cytokines for wound healing.

This invention is useful in the treatment of non-infected burn wounds, diabetic foot ulcers, venous leg ulcers and other types of chronic skin wounds. It’s helpful in the healing and regeneration of skin tissue.

US Patent No.: US 15/081,202
Date of Patent Granted: January 2019
Title of the Patent: Ready to Use, Hydrophilic, Self-dispersive, Fragmentable, and Biodegradable Porous Sponge Matrix and a Method of Manufacturing Thereof

Brand: VELNEZ
The 6^th patent is for the invention related to a porous absorbent Composite Material, which may be used e.g. in the form of a plug or tampon, for instance for packing antrum or other cavities of the body. As it is a hydrophilic Self-Dispersive, fragmentable and Bio-Absorbable Porous Composite foam it is helpful in controlling bleeding, wound closure, prevents tissue adhesion and/or support tissue regeneration.

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Velfour® is a revolutionary 4-layer compression bandaging system designed to manage venous leg ulcers and associated conditions. With a sub-bandage pressure of 35-40 mm Hg at the ankle, this high-compression system incorporates elastic layers to achieve sustained compression and promote healing.

Velfour® consists of four essential components that work together synergistically to deliver effective compression and support:

1. Velfour®#1 (Orthopaedic wool):

This layer serves as the primary absorbent material, effectively managing exudate while redistributing pressure evenly around the limb.

2. Velfour® #2 (Cotton crepe bandage):

Designed to enhance absorbency, the cotton crepe bandage smooths out the Orthopaedic Wool layer, ensuring optimal comfort and performance.

3. Velfour®#3 (Elastic Compression Bandage):

The first layer of elastic compression sub-bandage, exerting a pressure of approximately 17 mm Hg at the ankle. This layer provides the initial compression necessary for effective treatment.

4. Velfour® #4 (Cohesive Bandage):

The second layer of compression, adding the remaining 23 mm Hg of pressure while ensuring the bandage remains securely in place. The cohesive properties of this bandage contribute to its stability and adherence.

Velfour® offers a range of features and benefits that make it an exceptional choice for venous leg ulcer management:

1. Effective compression:

With a pressure of approximately 40 mm Hg at the ankle, it delivers the necessary compression to promote healing, gradually reducing to 17 mm Hg at the knee. This graduated compression approach ensures optimal therapeutic results.

2. Graduated compression:

The bandage provides high compression at the ankle and gradually decreases the pressure at the calf.

3. Sustained compression:

It maintains a consistent level of compression for up to a full week, allowing for uninterrupted therapy and reducing the frequency of bandage changes. The treatment process is made simpler by this feature, which also increases patient compliance.

The leading option for treating venous leg ulcers, Velfour® also has additional advantages for a number of other ailments, such as:

1. Treatment of Venous Ulcers:

It improves results by hastening the healing process and facilitating the closure of venous leg ulcers.

2. Prevention of Ulcer Recurrence:

In cases where traditional compression stockings are not tolerated, It provides an effective alternative for preventing the recurrence of venous ulcers.

3. Symptomatic Relief of Superficial Thrombophlebitis:

The compression offered by Velfour®alleviates pain and inflammation associated with superficial thrombophlebitis, providing much-needed comfort to patients.

4. Traumatic Wounds with Local Edema:

It aids in reducing edema and promoting the healing of traumatic wounds, helping to restore the affected area to its optimal state.

5. Venous/Lymphatic Disorders:

It is suitable for managing various venous and lymphatic disorders by providing effective compression and support.

To ensure the optimal application and use of Velfour®, it is essential to follow these guidelines:

1. Limb Assessment:

Accurate measurement of the ankle circumference is crucial to determine the appropriate combination of bandages needed. Any changes in limb contour should also be noted for reference.

2. Wound Assessment:

Mapping the ulcer provides a baseline to track progress throughout the treatment. Regular wound assessment enables healthcare professionals to evaluate the effectiveness of Velfour® and make necessary adjustments.

3. Pain Assessment:

This plays a crucial role in managing venous leg ulcers. Compression therapy with it can alleviate pain, although a slight increase may occur initially.

Velfour® stands as a game-changing solution for managing venous leg ulcers. Its innovative 4-layer compression bandage system, combined with its effective pressure distribution and sustained compression, offers unparalleled benefits for patients and healthcare professionals alike.

We are committed to providing valuable information and insights to support your journey towards improved wound healing and patient well-being.

Allergies are a common health issue that affect a significant portion of the population worldwide. Allergies are a hypersensitive reaction of the immune system to an otherwise harmless substance, which is known as an allergen. The allergen can be any substance that triggers an allergic reaction in the body, such as pollen, dust, food, or animal dander.

Allergies are caused due to the abnormal response of the immune system, which mistakes a harmless substance for a harmful invader and initiates a defence mechanism, called antibodies, to protect the body from it. This results in various allergic reactions, such as skin rashes, itching, sneezing, watery eyes, and in severe cases, anaphylaxis.

There are various reasons behind the occurrence of allergies. Genetics plays a significant role in determining an individual’s likelihood of developing allergies. Environmental factors such as exposure to pollution, chemicals, and toxins can also trigger allergies.

There are several different types of allergies, each with their unique symptoms and triggers.

Some of the most common types of allergies include:

1. Respiratory allergies:

These allergies are triggered by airborne allergens such as pollen, dust mites, and animal dander. The symptoms of respiratory allergies include sneezing, coughing, and wheezing.

2. Food allergies:

These allergies occur when the immune system reacts to certain foods, such as nuts, shellfish, and eggs. Symptoms of food allergies can range from mild itching, tingling in the mouth, hives, swelling of the lips, tongue, face or throat to more severe life-threatening anaphylaxis.

3. Skin allergies:

These allergies occur when the skin comes into contact with an allergen, such as certain fabrics, metals, or cosmetics. The symptoms of skin allergies include rashes, itching, and swelling.

4. Insect allergies:

These allergies occur when an individual is bitten or stung by an insect, such as bees or mosquitoes. The symptoms of insect allergies can range from mild itching to severe anaphylaxis.

5. Medicine allergies:

Medicine allergies are hypersensitive reactions of the immune system to certain medications. They can cause symptoms like skin rashes, itching, swelling, and in severe cases, difficulty breathing or anaphylaxis. It is important to communicate medicine allergies to healthcare providers to ensure safe and effective treatment.

Precautionary methods can be taken to manage allergies. Firstly, it is crucial to identify the allergen that triggers the allergic reaction. This can be done through various tests such as skin tests or blood tests. Once the allergen is identified, it is essential to avoid exposure to it. For example, individuals with food allergies must avoid eating the allergen-containing food.

Similarly, those with respiratory allergies must avoid exposure to airborne allergens, such as pollen or animal dander. If a person has a known severe allergy then they can also wear a medical alert bracelet, which lets others know that you have a serious allergy incase they are unable to communicate it.

Medications such as antihistamines, decongestants, and corticosteroids can be used to manage allergy symptoms. In severe cases, epinephrine injections may be required to manage anaphylaxis.

In addition to medication, several lifestyle changes can also help manage allergies. One of the most important being to try to reduce stress levels. While stress can’t trigger an allergic reaction it can make it worse if you are having one. When in stress your body releases hormones including histamine, which is a powerful chemical that leads to allergy symptoms thus making the reaction worse.

Allergies can significantly impact the lives of those who suffer from them. However, with proper management, it is possible to reduce the severity of allergy symptoms. If you suspect that you have an allergy, it is important to seek medical advice and get a proper diagnosis.

We advice to follow precautionary methods and working with a healthcare professional, that can help you manage allergies and improve your quality of life. Follow us for more such information.