Healthcare-associated infections (HAIs) are one of the most prevailing adverse events among hospitalized patients. These nosocomial infections are a leading cause of morbidity and mortality among critically ill hospitalized patients, especially in intensive care units (ICUs).

The most serious among these infections develop at the vascular access sites and are called as the Central Venous Catheter-associated Bloodstream Infections (CVC-BSIs) or may also be labeled as the Catheter-Related Blood Stream Infections (CRBSI).