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Depression More than a Brain Chemical Imbalance
Depression More than a Brain Chemical Imbalance

When you are feeling sad for a prolonged period of time and you can’t find any specific reason for it, you might be in the clutches of depression and need to seek professional help. Depression is a common and a widely observed mental disorder which affects people of all ages.

As per WHO, more than 300 million people worldwide suffer from depression. You may not know that the person sitting next to you and laughing with you might be under the tight grip of depression.

People often feel reluctant to seek help. Therefore, it is a highly underdiagnosed and untreated problem. Let’s understand what depression is and how we can help our near ones suffering from depression.

Depression Defined:
Depression or major depressive disorder is a serious mood disorder accompanied by a never-ending sadness or loss of interest. Depression can lead to a variety of physical and emotional problems. These problems may affect how a person feels and behaves towards day-to-day activities. However, for a person to be diagnosed with depression, the symptoms must last for at least 2 weeks.

The symptoms of depression in adults differ from person to person, as no two people are affected the same way.

  1. Symptoms in children may include sadness, irritability, pain, clinginess, worry, refusing to go to school, or being underweight.
  2. Teenage symptoms of depression may include being sad, irritability, extremely sensitive, feeling negative, worthless & misunderstood, anger, poor performance at school, addiction to drugs or alcohol, self-harm, too much eating or sleeping, losing interest in normal activities, and avoiding social interaction.
  3. Symptoms in Adults may include the following:
    • Memory difficulties
    • Personality changes
    • Physical aches, Fatigue, loss of appetite, sleep problems or loss of interest in sex — not caused by any other medical condition or medications
    • Feeling excluded or dissociated
    • Suicidal thinking or feelings

Prolonged depression is one of the leading causes of suicide. What makes it dangerous is the fact that those who are suffering from depression are unpredictable.

As per WHO, nearly 8 lac people commit suicide every year making it the second leading cause of deaths among people aged 15-29 years.

What causes depression:
1. Brain Chemistry: Our brain uses chemical messengers called neurotransmitters to communicate with its other parts or nervous system. Any problem or imbalances in the brain related to neurotransmitters have been linked to depression. For example, a decrease in the production of some specific neurotransmitters like serotonin, dopamine & norepinephrine (noradrenaline) by the neurons is responsible for creating a depressed mood and stress.

2. Hormones imbalance: An imbalance in hormonal levels may trigger depression. For example, post-partum depression (peripartum depression) or depression resulting from thyroid problems, menopause (premenstrual dysphoric disorder) or other conditions.

3. Inherited traits: People with family history of depression are more likely to suffer from depression. Research is going on to find depression causing genes.

4. Biological differences & Personality: People who had faced depression prior in their lives appear to have some physical changes in their brains triggering the risk of being depressed. Pessimists and people with low self-esteem are also more likely to experience depression.

5. Environmental factors: An exposure to violence, stress, trauma, major life changes, abuses, poverty, neglect, rejection may increase the chances of depression.

Yes, it is treatable!

Depression is different for all those who are affected by it. There is no “one-size-fits-all” treatment method. It may take a while for the doctor to understand the symptoms and define the treatment methods. The sooner the treatment begins, the more effective it is.

Medications: Anti-depressants are effective for moderate to severe depression cases. The ultimate aim is to improve the brain’s ability to regulate mood. Antidepressants work by increasing the concentration of neurotransmitters in the synapse (space between two nerve cells or neurons through which information is passed from one neuron to another). These are selective serotonin reuptake inhibitors [SSRIs] and must not be considered as the first line of treatment for mild depression cases, and children.

Psychotherapies: Psychotherapies are also called “Talk Therapy” or “Counselling”. Several types of counselling techniques are available which could help the patients. For example, Behavioural Activation, Cognitive Behavioural Therapy [CBT], Problem Solving Therapy and Interpersonal Psychotherapy [IPT].

Brain Stimulation Therapies: Brain Stimulation Therapies like electroconvulsive therapy (ECT) work better in patients with severe depression where other treatment methods fail to work. ECT is also a good treatment option for pregnant women where medications might harm the foetus or in old age patients who can’t tolerate drug side effects. Other treatment modalities used to treat medication-resistant depression include repetitive transcranial magnetic stimulation (rTMS) and vagus nerve stimulation (VNS).

Beyond treatment:

Things we can do to support someone who’s depressed

- Be patient
- Be on their side: Convey a sense of understanding.
- Be Sympathetic: Avoid pointing out and accusatory tones.
- Offer to help
- Don’t criticize or judge or compare 

Depression shouldn’t be ignored for long. Measures need to be taken as soon as possible so as to avoid any unpleasant happening. Never leave a depressed person alone. Speaking one’s heart out can help to ease the burden to a great extent. Apart from that, see a doctor immediately.

Visit www.dattmedi.com for more infomation.
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How Your Body Repairs Itself

Wound healing is nothing short of a biological marvel. When your skin is injured, your body launches a meticulously coordinated process to restore its integrity and functionality.

Understanding this journey not only highlights the sophistication of our biology but also empowers us to care for wounds more effectively.

The Remarkable Phases of Wound Healing

Imagine you’ve just scraped your knee. 
What happens next might seem simple, but beneath the surface, your body is hard at work.
wound healing

Wound healing unfolds in four incredible stages:

1. Hemostasis (Minutes to Hours)

The moment an injury occurs, your body springs into action to stop the bleeding. Blood vessels constrict, and platelets rush to the scene to form a clot. This clot acts as a temporary seal, buying your body time to prepare for deeper repairs.

2. Inflammation (1–5 Days)

Next, your immune system steps in. Neutrophils and macrophages arrive to clear away debris and bacteria, ensuring the wound is clean and ready for rebuilding. The redness, swelling, and warmth you notice are signs of this vital repair work.

3. Proliferation (4–24 Days)

Now the real construction begins. Fibroblasts produce collagen to lay the foundation of new tissue, while blood vessels grow to supply nutrients and oxygen. You’ll see granulation tissue—pink and bumpy—as the wound starts to fill in, and new skin cells begin to migrate across the surface.

4. Maturation (21 Days to Months)

In the final phase, your body strengthens and remodels the new tissue. Collagen fibers are cross-linked for durability, and scar tissue forms. While scars may not have the same elasticity as uninjured skin, they are a testament to your body’s incredible ability to heal.

While the healing process is natural, it doesn’t occur in isolation.

A range of factors can either speed it up or slow it down:

  • Age and Health: Older age, diabetes, and immune disorders can delay healing.
  • Nutrition: Nutrients like protein, zinc, and vitamins C and E are essential for tissue repair.
  • Lifestyle Choices: Smoking and alcohol reduce oxygen supply to tissues, hindering recovery.
  • Wound Care: Proper hygiene and dressing techniques can prevent infection and promote faster healing.

Did you know
Keeping a wound moist can significantly speed up healing?

Moist wound

Moisture creates the perfect environment for cells to migrate and for granulation tissue to develop. Modern dressings, designed to maintain this balance, have revolutionized wound care by reducing healing times and minimizing scars.

Cutting-Edge Advances in Wound Care

Science continues to push the boundaries of what’s possible in wound healing. Some groundbreaking innovations include:

  • Growth Factors: These proteins supercharge the repair process, stimulating cell activity.
  • Biomaterials: From hydrogels to bioengineered skin substitutes, these materials mimic natural tissue to accelerate healing.
  • Stem Cell Therapy: Stem cells encourage the regeneration of complex tissues, offering hope for chronic wounds.
  • Hyperbaric Oxygen Therapy: By delivering concentrated oxygen, this therapy enhances cellular activity and reduces infection risk.

Supporting Your Body’s Natural Healing Powers

Healing isn’t just about what happens on a cellular level—your lifestyle choices play a critical role:

  • Eat Right: Protein-rich foods and micronutrients like zinc and vitamin C fuel the repair process.
  • Avoid Harmful Habits: Smoking and excessive alcohol consumption can severely impede healing.
  • Prioritize Rest: Quality sleep and stress management boost your immune system, giving your body the tools it needs to recover.
While most wounds heal naturally, some may require medical intervention. Watch for signs of delayed healing, such as persistent redness, swelling, or unusual odors. Chronic wounds or excessive scarring, like keloids, might benefit from specialized treatments.

The journey of wound healing is a testament to the resilience of the human body. Each phase, from hemostasis to maturation, reflects a symphony of biological processes working in harmony. By caring for your wounds and supporting your body’s natural abilities, you can pave the way for smoother, faster recoveries. And with the advancements in medical science, the future of wound care looks brighter than ever.

Chronic Pain Living Better Every Day

Chronic pain is a pervasive issue that affects millions of individuals worldwide, significantly altering their daily lives and overall well-being. Unlike acute pain, which serves as a signal of injury or illness and typically subsides with treatment, chronic pain persists for weeks, months, or even years. This relentless discomfort can arise from various conditions such as arthritis, fibromyalgia, and nerve damage. The impact of chronic pain extends beyond the physical realm, often leading to emotional distress and reduced quality of life.

In this blog, we will delve into effective strategies for managing chronic pain, focusing on coping techniques, nutrition, emotional well-being, and lifestyle adaptations. By understanding and addressing the multifaceted nature of chronic pain, individuals can improve their daily lives and enhance their overall health.

Coping Strategies and Techniques:

Managing chronic pain involves various coping mechanisms. Mindfulness and relaxation techniques, such as meditation and progressive muscle relaxation, can help reduce pain perception. Breathing exercises, like deep breathing or diaphragmatic breathing, also provide relief. Regular physical activity, tailored to your condition, can improve flexibility and strength, reducing pain over time. Activities such as swimming, walking, and yoga are often recommended for their low-impact benefits.

Nutrition and Diet:

Nutrition plays a vital role in managing inflammation and pain. Anti-inflammatory foods, such as leafy greens, fatty fish, nuts, seeds, and berries, can help alleviate symptoms. Omega-3 fatty acids, found in fish and flaxseeds, are particularly beneficial. Conversely, avoiding processed foods, sugary snacks, and excessive caffeine is crucial as they can exacerbate inflammation and pain. Staying hydrated and maintaining a balanced diet support overall health and pain management.

Emotional Well-being:

Chronic pain takes an emotional toll, often leading to anxiety, depression, and stress. Supporting mental health through therapy, such as cognitive-behavioral therapy (CBT), can be effective. CBT helps in changing negative thought patterns and developing coping strategies. Seeking social support from friends, family, or support groups can provide comfort and understanding. Engaging in hobbies, practicing mindfulness, and using relaxation techniques can help manage stress and improve emotional resilience.

Adapting Daily Life:

Adapting daily routines can enhance quality of life. Using assistive devices like ergonomic furniture, mobility aids, and adaptive tools can make daily tasks easier and more comfortable. Prioritizing rest and pacing activities throughout the day can prevent flare-ups and manage energy levels. Organizing your environment to minimize unnecessary strain and setting realistic goals for activities can help maintain a balance between activity and rest.

By understanding chronic pain and implementing these strategies, you can live a more fulfilling life despite the challenges. Managing chronic pain requires a holistic approach that addresses physical, emotional, and lifestyle factors, empowering you to live better every day.

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