Patent No.:
US 10, 076, 552 B2
Date of the Patent Granted: Sep. 18, 2018
Title of the Patent: MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION MANUFACTURING THEREOF

What is Wound Healing & need of the Invention:
Wound Healing is a complex process in which the injured tissue is repaired & regenerated and new tissues are formed. The whole process involves three different phases: inflammation, proliferative and remodeling. Each of these phases is controlled and regulated by biologically active substances called growth factors.

These growth factors are hormone-like molecules that interact with specific cell surface receptors to control the process of tissue repair. The research shows that re-epithelialization is enhanced by the presence of occlusive wound dressings which maintain a moisture barrier.

There are different treatment modalities available for the treatment of wounds and ulcers ranging from antibiotics, occlusive layers, bandages, poultices, mechanical devices that reduce evaporation of water and many others.

The major drawback of these treatment methods is that they enhance wound healing by supporting the body mechanisms to heal the wound. If the patient will have compromised immunity or other body functions that may not work optimally, wound healing will not take place or will be delayed. This may limit the mobility of the patient and lower the quality of life.

There is a need of the treatment method which could actively regenerate the skin, dermis and epidermis. We @ Datt Mediproducts have developed an innovative herbal based antimicrobial dressing which reduce the microflora in wounds and actively promotes healing by stimulating stem cells that are present even in deep wounds and enhance the migration of fibroblast and keratinocytes and secretion of growth factors.

ABOUT THE INVENTION:
The invention involves polymer chemistry and herbal formulation preparation for the treatment of compromised tissues like infected wounds, burn wounds and ulcers in both humans and animals. It is used as a topical device for a range of indications including anti – cancer transdermal patch for melanoma therapy, superbugs infected tropical wounds and multiple sclerosis also.

The invention is composed of a water solubilized nano-sized formulation of a non-aqueous extract of phyto-pharmaceuticals, animal or synthetic biocompatible gel or on matrix coated or both.

 SUMMARY OF THE INVENTION:
The present invention provides a wound healing matrix comprising of a variety of natural ingredients, all working together in a synergistic way to promote wound healing by stimulating the stem cells. Stem cells have a great potential of cell division and are ultimately responsible for the homeostasis of steady state tissues.

Stem cells are normally slow cycling. However, there proliferation can be stimulated by certain growth factors. For example, cytokines such as Tumor Necrosis Factor (TNF), Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF) and Interleukin-1 (IL-1) are believed to be useful.

The present invention consists of different herbs and synthetic biopolymers which are helpful in relieving pain, providing a soothing effect, and healing the wounds upon repeated use by providing a moist healing environment and stimulating the stem cells to regenerate the lost tissues.

The transdermal patch formulated with phytopharmaceutical preparation is intended for transdermal delivery system preferably for cancer therapy either individually or the combination.

Advantages of the Invention:

  • It provides a multi-purpose wound healing matrix with a bandage for compromised tissues viz. skin having wounds or melanoma.
  • Enhanced bioavailability of its individual components, working together in a synergistic way.
  • Another promising advantage of this phytopharmaceutical invention is that it displays minimal side effects in clinical applications of the drug.
  • Since the components in the formulation are from herbal / natural resources, it is very safe and eco – friendly and does not produce any adverse effect on the skin.

Following are the broad range of applications:

  • Anti-microbial
  • Anti-inflammatory
  • Analgesic
  • Antioxidant
  • Wound healing
  • Radiation poisoning
  • Modulates immunity
  • Biocompatible
  • Haemostatic
  • Nano based technology for drug releasing
  • Anti-cancer properties
  • Multiple sclerosis

Follow us @Datt Mediproducts to know more about such innovative patented.

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Wound Care in Emergency Situations: Quick Response Tips

In moments of crisis, such as accidents or emergencies, being equipped with the knowledge and skills to administer proper wound care can make a critical difference in saving lives and preventing further complications.

Whether you’re a bystander or the injured person themselves, understanding the essential steps of wound care in emergency situations is paramount. 

Here are some quick response tips to guide you through assessing and managing wounds effectively:

Assessment and Safety First:
The foremost priority in any emergency situation is safety. Before rushing to aid the injured person, take a moment to assess the surroundings for potential hazards. Ensure both your safety and that of the injured individual by identifying and eliminating any immediate dangers.

Control Bleeding:
One of the most crucial steps in wound care is controlling bleeding. Apply direct pressure to the wound using a clean cloth or dressing. Elevating the injured area, if feasible, can help reduce blood flow and minimize bleeding. Prompt action in staunching the blood flow can prevent further loss and stabilize the individual’s condition.

Clean the Wound Quickly:
After addressing the bleeding, it’s essential to clean the wound promptly. Rinse the wound gently with clean water to remove any debris or foreign objects. In emergency situations, it’s advisable to avoid using strong antiseptics or solutions unless absolutely necessary, as they can cause further irritation or delay in treatment.

Apply Dressing and Bandage:
Once the wound is cleaned, cover it with a sterile dressing or a clean cloth to protect it from contamination. Secure the dressing in place using a bandage or cloth, ensuring it is snug but not too tight to impede circulation. Proper dressings help create an optimal environment for wound healing while preventing infection.

Seek Medical Assistance:
While initial wound care is essential, it’s crucial to recognize the severity of the injury and seek professional medical assistance promptly. Call emergency services or transport the individual to the nearest medical facility if the wound is severe, deep, or if bleeding persists despite initial measures. Timely medical intervention can prevent complications and facilitate proper wound management.

Prevent Shock and Comfort the Injured:
In addition to physical care, it’s vital to address the emotional and psychological needs of the injured person. Keep them calm and reassured to prevent shock, covering them with a blanket to maintain body warmth and comfort. Offering words of encouragement and support can go a long way in alleviating distress.

Continued Monitoring and Updates:
Even after administering initial first aid, it’s essential to continue monitoring the injured person’s condition until professional help arrives. Stay vigilant for any signs of deterioration or changes in vital signs, providing updates and relevant information to emergency responders upon their arrival. Your ongoing support and assistance can contribute significantly to the individual’s overall well-being and recovery.

Therefore, effective wound care in emergency situations requires a combination of swift action, sound judgment, and compassion. By prioritizing safety, controlling bleeding, cleaning the wound, seeking medical assistance, providing comfort, and monitoring the individual’s condition, you can help ensure the best possible outcome for the injured person. Remember, every second counts in an emergency, and your actions can make a lifesaving difference.

For more information on our comprehensive range of wound care products, including Antimicrobial Dressings, Compression Bandages, and Film & post-operative Dressings, Visit www.dattmedi.com for more information.

Understanding Parkinson's Disease: Symptoms, Causes, and Treatment Options

Parkinson’s disease is a complex and often misunderstood neurodegenerative disorder that affects millions of people worldwide. It is characterized by a progressive loss of dopamine-producing cells in the brain, leading to a range of motor and non-motor symptoms that can significantly impact daily life.

In this blog, we will explore the symptoms, causes, and treatment options for Parkinson’s disease, as well as the importance of support and advocacy for those living with the condition.

Symptoms of Parkinson’s Disease

Parkinson’s disease primarily affects movement, causing a variety of motor symptoms that can vary in severity from person to person. The most common symptoms include tremors, stiffness, and bradykinesia (slowness of movement). Individuals with Parkinson’s may also experience freezing gait, a sudden inability to initiate or continue walking, as well as a stooped posture and changes in speech and handwriting.

In addition to motor symptoms, Parkinson’s disease can also cause a range of non-motor symptoms that may be less visible but equally challenging. These can include depression, anxiety, cognitive impairment, sleep disturbances, and autonomic dysfunction. It is important for individuals with Parkinson’s and their caregivers to be aware of these non-motor symptoms and seek appropriate support and management strategies.

Causes and Risk Factors

The exact cause of Parkinson’s disease is not yet fully understood, but it is believed to involve a combination of genetic and environmental factors. Advancing age is the most significant risk factor, with the majority of cases diagnosed in people over the age of 60. However, younger individuals can also develop Parkinson’s, particularly if they have a family history of the disease or are exposed to certain environmental toxins such as pesticides and solvents.

Recent research has also identified specific genetic mutations associated with an increased risk of Parkinson’s disease, although these account for only a small percentage of cases. Overall, Parkinson’s is thought to result from a complex interplay of genetic susceptibility and environmental triggers, and further research is needed to fully understand these mechanisms.

Treatment Options and Management Strategies

While there is currently no cure for Parkinson’s disease, there are a variety of treatments available to help manage symptoms and improve quality of life. Medications such as levodopa, dopamine agonists, and MAO-B inhibitors can help alleviate motor symptoms by increasing dopamine levels in the brain. Physical therapy, occupational therapy, and speech therapy can also be beneficial in addressing specific motor and non-motor symptoms.

In addition to medical interventions, lifestyle modifications such as regular exercise, healthy diet, and stress management techniques can also play a key role in managing Parkinson’s disease. Social support and community resources are also invaluable for individuals living with Parkinson’s and their caregivers, providing emotional support, practical assistance, and opportunities for socialization.

Support and Advocacy

In India, there are several organizations dedicated to supporting individuals with Parkinson’s disease and raising awareness about the condition. One such organization is the Parkinson’s Disease and Movement Disorder Society (PDMDS), which offers rehabilitation programs, support groups, and educational resources for people living with Parkinson’s and their families. The Indian Parkinson’s Disease Association (IPDA) is another valuable resource, providing information, advocacy, and support services to improve the lives of those affected by Parkinson’s disease.

Parkinson’s disease is a challenging and complex condition that requires a comprehensive approach to management and care. By understanding the symptoms, causes, and treatment options for Parkinson’s, as well as the importance of support and advocacy, we can work together to improve the lives of individuals living with this condition. Through education, awareness, and community involvement, we can make a difference in the lives of those affected by Parkinson’s disease.

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