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US Patent Granted For A Novel Herbal Dressing


Patent No.: US 10, 076, 552 B2
Date of the Patent Granted: Sep. 18, 2018
Title of the Patent: MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION MANUFACTURING THEREOF

What is Wound Healing & need of the Invention:
Wound Healing is a complex process in which the injured tissue is repaired & regenerated and new tissues are formed. The whole process involves three different phases: inflammation, proliferative and remodeling. Each of these phases is controlled and regulated by biologically active substances called growth factors.

These growth factors are hormone-like molecules that interact with specific cell surface receptors to control the process of tissue repair. The research shows that re-epithelialization is enhanced by the presence of occlusive wound dressings which maintain a moisture barrier.

There are different treatment modalities available for the treatment of wounds and ulcers ranging from antibiotics, occlusive layers, bandages, poultices, mechanical devices that reduce evaporation of water and many others.

The major drawback of these treatment methods is that they enhance wound healing by supporting the body mechanisms to heal the wound. If the patient will have compromised immunity or other body functions that may not work optimally, wound healing will not take place or will be delayed. This may limit the mobility of the patient and lower the quality of life.

There is a need of the treatment method which could actively regenerate the skin, dermis and epidermis. We @ Datt Mediproducts have developed an innovative herbal based antimicrobial dressing which reduce the microflora in wounds and actively promotes healing by stimulating stem cells that are present even in deep wounds and enhance the migration of fibroblast and keratinocytes and secretion of growth factors.

ABOUT THE INVENTION:
The invention involves polymer chemistry and herbal formulation preparation for the treatment of compromised tissues like infected wounds, burn wounds and ulcers in both humans and animals. It is used as a topical device for a range of indications including anti – cancer transdermal patch for melanoma therapy, superbugs infected tropical wounds and multiple sclerosis also.

The invention is composed of a water solubilized nano-sized formulation of a non-aqueous extract of phyto-pharmaceuticals, animal or synthetic biocompatible gel or on matrix coated or both.

 SUMMARY OF THE INVENTION:
The present invention provides a wound healing matrix comprising of a variety of natural ingredients, all working together in a synergistic way to promote wound healing by stimulating the stem cells. Stem cells have a great potential of cell division and are ultimately responsible for the homeostasis of steady state tissues.

Stem cells are normally slow cycling. However, there proliferation can be stimulated by certain growth factors. For example, cytokines such as Tumor Necrosis Factor (TNF), Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF) and Interleukin-1 (IL-1) are believed to be useful.

The present invention consists of different herbs and synthetic biopolymers which are helpful in relieving pain, providing a soothing effect, and healing the wounds upon repeated use by providing a moist healing environment and stimulating the stem cells to regenerate the lost tissues.

The transdermal patch formulated with phytopharmaceutical preparation is intended for transdermal delivery system preferably for cancer therapy either individually or the combination.

Advantages of the Invention:

  • It provides a multi-purpose wound healing matrix with a bandage for compromised tissues viz. skin having wounds or melanoma.
  • Enhanced bioavailability of its individual components, working together in a synergistic way.
  • Another promising advantage of this phytopharmaceutical invention is that it displays minimal side effects in clinical applications of the drug.
  • Since the components in the formulation are from herbal / natural resources, it is very safe and eco – friendly and does not produce any adverse effect on the skin.

Following are the broad range of applications:

  • Anti-microbial
  • Anti-inflammatory
  • Analgesic
  • Antioxidant
  • Wound healing
  • Radiation poisoning
  • Modulates immunity
  • Biocompatible
  • Haemostatic
  • Nano based technology for drug releasing
  • Anti-cancer properties
  • Multiple sclerosis

Follow us @Datt Mediproducts to know more about such innovative patented.

Visit www.dattmedi.com for more infomation.
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Advantages of Using Velfix®࿯ T+Pad for Post Surgical Wounds

In the field of post-surgical wound care, innovation plays a crucial role in ensuring optimal healing outcomes and patient comfort. Introducing Velfix® -T+Pad, a groundbreaking solution that redefines the standards of wound dressings. Meticulously designed and crafted, Velfix® -T+Pad stands at the forefront of advanced wound care technology, offering not only healing but also unparalleled comfort and convenience.

Waterproof and Bacterial Barrier Properties:

Among the essential features of wound dressings, waterproofing and bacterial barrier stand out. Velfix® -T+Pad not only meets these requirements but surpasses them. Its impermeable yet breathable film forms a protective shield against water and bacteria, safeguarding the wound from external threats and fostering a hygienic healing environment.

Benefits of Continuous Visual Monitoring: 

The advantage of transparent film dressings is the ability to visually monitor the wound without removing the dressing. This allows healthcare providers to detect early signs of infection: clinicians can quickly spot signs of infection, excessive drainage, or other complications, facilitating prompt intervention. It also aids in exudate management : ensuring that the wound exudate is being effectively absorbed and does not pose a risk to the healing process.

Conforming to Body Contours:

Comfort is paramount, especially in areas prone to movement or swelling. Velfix® -T+Pad addresses this need adeptly. Its flexible design seamlessly conforms to the body’s contours, providing a snug fit without compromising comfort. Whether it’s a joint, a curve, or a crease, Velfix® -T+Pad stays in place, ensuring uninterrupted healing.

Effective Evaporation of Moisture:

Moisture management is critical for wound healing, and Velfix® -T+Pad excels in this aspect. Thanks to its innovative adhesive pattern, it facilitates efficient moisture evaporation from the wound bed. This not only keeps the area dry but also prevents maceration, creating optimal conditions for healing.

Reducing Pain Upon Removal:

Dressing changes can be painful, but Velfix® -T+Pad aims to alleviate this discomfort. Featuring a non-adherent pad, it minimizes trauma upon removal, reducing pain and discomfort for the patient. With Velfix® -T+Pad, dressing changes become a smoother, more tolerable process, enhancing the overall patient experience.

In the realm of post-surgical wound care, excellence is imperative. With its innovative design and advanced technology, Velfix® -T+Pad sets a new standard for wound dressings, offering a comprehensive solution that prioritizes healing, comfort, and convenience. 

From its waterproof and bacterial barrier properties to its transparent film for easy monitoring, Velfix® -T+Pad epitomizes cutting-edge wound care. Trust in Velfix® -T+Pad to deliver not only healing but also peace of mind, ensuring a smoother, swiffer path to recovery for patients worldwide.

In the realm of wound care, continuous advancements are constantly improving the way we treat and manage various types of wounds. Among the latest innovations, Velseal® -T Disc has emerged as a game-changer. This revolutionary product offers an effective and convenient solution for promoting wound healing and enhancing patient comfort.

Understanding Velseal® -T Disc

It is a cutting-edge wound care product designed to optimize the healing process while minimizing discomfort for patients. Velseal® -T Disc promotes haemostasis by absorbing the blood and accumulates clotting factor within the voids and initiate the clotting by interaction with Thrombin, Calcium chloride and Tranexamic acid.

Key Features and Benefits:

1. Advanced Composition:

It is composed of high-quality materials that offer excellent absorption and retention capacities, reducing the risk of maceration and infection. However, it does not provide moisture balance or directly contribute to wound healing.

2. Easy Application:

Thee disc-shaped design of Velseal® -T Disc allows for simple and hassle-free application. Its non-adherent nature eliminates the need for additional fixation methods, providing a secure and comfortable fit. The dressing is available in various sizes to accommodate different wound types and locations.

3. Enhanced Patient Comfort:

It prioritizes patient comfort by minimizing pain and trauma during dressing changes. The non-adherent surface prevents the dressing from sticking to the wound bed, reducing discomfort and potential damage to healing tissue.

4. Cost-Effective Solution:

It offers a cost-effective wound care solution, as it requires no dressing changes. A single application helps in achieving complete hemostasis, contributing to overall healthcare cost savings. Its durability and prolonged wear time further enhance its cost-effectiveness.

Clinical Efficacy and Evidence

The product has undergone rigorous testing and evaluation to validate its clinical efficacy. Clinical studies have demonstrated its effectiveness in promoting faster wound healing, reducing pain, and minimizing complications such as infection. These studies highlight the dressing’s superior moisture management capabilities and its ability to facilitate granulation tissue formation, resulting in improved patient outcomes.

In the rapidly evolving field of wound care, the Velseal® -T Disc stands out as a remarkable innovation. Its unique composition, easy application, and patient-centric design make it a valuable addition to any healthcare setting. With its demonstrated clinical efficacy and cost-effectiveness, this advanced dressing offers a promising solution for healthcare professionals and patients alike. By leveraging the benefits of Velseal® -T Disc, healthcare providers can enhance wound healing outcomes and improve the overall quality of care for patients with acute or chronic wounds.