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US Patent Granted for a Novel Herbal Dressing

Patent No.: US 10, 076, 552 B2
Date of the Patent Granted: Sep. 18, 2018
Title of the Patent: MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION MANUFACTURING THEREOF

What is Wound Healing & need of the Invention:
Wound Healing is a complex process in which the injured tissue is repaired & regenerated and new tissues are formed. The whole process involves three different phases: inflammation, proliferative and remodeling. Each of these phases is controlled and regulated by biologically active substances called growth factors.

These growth factors are hormone-like molecules that interact with specific cell surface receptors to control the process of tissue repair. The research shows that re-epithelialization is enhanced by the presence of occlusive wound dressings which maintain a moisture barrier.

There are different treatment modalities available for the treatment of wounds and ulcers ranging from antibiotics, occlusive layers, bandages, poultices, mechanical devices that reduce evaporation of water and many others.

The major drawback of these treatment methods is that they enhance wound healing by supporting the body mechanisms to heal the wound. If the patient will have compromised immunity or other body functions that may not work optimally, wound healing will not take place or will be delayed. This may limit the mobility of the patient and lower the quality of life.

There is a need of the treatment method which could actively regenerate the skin, dermis and epidermis. We @ Datt Mediproducts have developed an innovative herbal based antimicrobial dressing which reduce the microflora in wounds and actively promotes healing by stimulating stem cells that are present even in deep wounds and enhance the migration of fibroblast and keratinocytes and secretion of growth factors.

ABOUT THE INVENTION:
The invention involves polymer chemistry and herbal formulation preparation for the treatment of compromised tissues like infected wounds, burn wounds and ulcers in both humans and animals. It is used as a topical device for a range of indications including anti – cancer transdermal patch for melanoma therapy, superbugs infected tropical wounds and multiple sclerosis also.

The invention is composed of a water solubilized nano-sized formulation of a non-aqueous extract of phyto-pharmaceuticals, animal or synthetic biocompatible gel or on matrix coated or both.

SUMMARY OF THE INVENTION:
The present invention provides a wound healing matrix comprising of a variety of natural ingredients, all working together in a synergistic way to promote wound healing by stimulating the stem cells. Stem cells have a great potential of cell division and are ultimately responsible for the homeostasis of steady state tissues.

Stem cells are normally slow cycling. However, there proliferation can be stimulated by certain growth factors. For example, cytokines such as Tumor Necrosis Factor (TNF), Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF) and Interleukin-1 (IL-1) are believed to be useful.

The present invention consists of different herbs and synthetic biopolymers which are helpful in relieving pain, providing a soothing effect, and healing the wounds upon repeated use by providing a moist healing environment and stimulating the stem cells to regenerate the lost tissues.

The transdermal patch formulated with phytopharmaceutical preparation is intended for transdermal delivery system preferably for cancer therapy either individually or the combination.

Advantages of the Invention:

It provides a multi-purpose wound healing matrix with a bandage for compromised tissues viz. skin having wounds or melanoma.
Enhanced bioavailability of its individual components, working together in a synergistic way.
Another promising advantage of this phytopharmaceutical invention is that it displays minimal side effects in clinical applications of the drug.
Since the components in the formulation are from herbal / natural resources, it is very safe and eco – friendly and does not produce any adverse effect on the skin.

Following are the broad range of applications:

Anti-microbial
Anti-inflammatory
Analgesic
Antioxidant
Wound healing
Radiation poisoning
Modulates immunity
Biocompatible
Haemostatic
Nano based technology for drug releasing
Anti-cancer properties
Multiple sclerosis

Follow us @Datt Mediproducts to know more about such innovative patented.

Visit www.dattmedi.com for more infomation.

Chronic pain is a pervasive issue that affects millions of individuals worldwide, significantly altering their daily lives and overall well-being. Unlike acute pain, which serves as a signal of injury or illness and typically subsides with treatment, chronic pain persists for weeks, months, or even years. This relentless discomfort can arise from various conditions such as arthritis, fibromyalgia, and nerve damage. The impact of chronic pain extends beyond the physical realm, often leading to emotional distress and reduced quality of life.

In this blog, we will delve into effective strategies for managing chronic pain, focusing on coping techniques, nutrition, emotional well-being, and lifestyle adaptations. By understanding and addressing the multifaceted nature of chronic pain, individuals can improve their daily lives and enhance their overall health.

Coping Strategies and Techniques:

Managing chronic pain involves various coping mechanisms. Mindfulness and relaxation techniques, such as meditation and progressive muscle relaxation, can help reduce pain perception. Breathing exercises, like deep breathing or diaphragmatic breathing, also provide relief. Regular physical activity, tailored to your condition, can improve flexibility and strength, reducing pain over time. Activities such as swimming, walking, and yoga are often recommended for their low-impact benefits.

Nutrition and Diet:

Nutrition plays a vital role in managing inflammation and pain. Anti-inflammatory foods, such as leafy greens, fatty fish, nuts, seeds, and berries, can help alleviate symptoms. Omega-3 fatty acids, found in fish and flaxseeds, are particularly beneficial. Conversely, avoiding processed foods, sugary snacks, and excessive caffeine is crucial as they can exacerbate inflammation and pain. Staying hydrated and maintaining a balanced diet support overall health and pain management.

Emotional Well-being:

Chronic pain takes an emotional toll, often leading to anxiety, depression, and stress. Supporting mental health through therapy, such as cognitive-behavioral therapy (CBT), can be effective. CBT helps in changing negative thought patterns and developing coping strategies. Seeking social support from friends, family, or support groups can provide comfort and understanding. Engaging in hobbies, practicing mindfulness, and using relaxation techniques can help manage stress and improve emotional resilience.

Adapting Daily Life:

Adapting daily routines can enhance quality of life. Using assistive devices like ergonomic furniture, mobility aids, and adaptive tools can make daily tasks easier and more comfortable. Prioritizing rest and pacing activities throughout the day can prevent flare-ups and manage energy levels. Organizing your environment to minimize unnecessary strain and setting realistic goals for activities can help maintain a balance between activity and rest.

By understanding chronic pain and implementing these strategies, you can live a more fulfilling life despite the challenges. Managing chronic pain requires a holistic approach that addresses physical, emotional, and lifestyle factors, empowering you to live better every day.

When it comes to managing fractures, the choice of cast material can make a significant difference in a patient’s recovery experience. Orthopaedic casts are essential in ensuring that broken bones heal correctly by providing the necessary immobilization. Two popular options in the medical field are Fiberglass and Plaster of Paris (POP) bandages. But how do they compare? Let’s dive into the details.

A. Material Composition: The Building Blocks

The fundamental difference between these two types of bandages begins with what they are made of:

Fiberglass is a synthetic material, made from plastic fibers coated with a resin. It’s known for being lightweight and is often available in various colors, which can add a bit of personality to an otherwise clinical experience.
Plaster of Paris is made from a fine white powder called gypsum. When mixed with water, it forms a thick paste that hardens as it dries.

B. Application Process: Ease vs. Skill

Applying these bandages requires different techniques:

Fiberglass bandages are dipped in water, applied to the injury, and begin hardening almost immediately, which allows for quick and efficient application. This makes it easier for healthcare providers to mold it perfectly to the patient’s body.
Plaster of Paris bandages need to be soaked in water and take longer to set. While they require more skill to apply, they offer a smooth finish that many patients find comfortable.

C. Durability and Strength: Which Lasts Longer?

When considering durability:

Fiberglass is the champion of strength. Its resistance to wear and tear makes it ideal for active individuals or cases requiring long-term immobilization.
Plaster of Paris is less durable, with a tendency to chip over time, making it better suited for short-term casts or initial treatments.

D. Comfort and Breathability: Feeling at Ease

Comfort is a top priority for patients who need to wear a cast for an extended period:

Fiberglass is lighter and less bulky, which adds to the patient’s comfort. However, it can sometimes be less breathable, leading to potential discomfort in hot or humid climates.
Plaster of Paris is bulkier and heavier, but it’s smooth finish can be more comfortable for some, allowing the skin to breathe better.

E. Setting Time and Ease of Use: Quick vs. Steady

The time it takes for a cast to set is crucial:

Fiberglass sets in just a few minutes, enabling patients to resume limited activities sooner.
Plaster of Paris takes much longer, often up to 15 minutes, which can be a disadvantage when immediate mobility is needed.

F. Water Resistance and Hygiene: Keeping It Clean

Hygiene is another critical factor:

Fiberglass is water-resistant, making it easier to maintain and less likely to harbour bacteria.
Plaster of Paris does not resist water and can easily disintegrate if exposed to moisture, requiring patients to take extra precautions to keep it dry.

G. Cost and Accessibility: Budget Matters

Cost and availability can influence the choice:

Fiberglass is typically more expensive and may not be available in all healthcare settings.
Plaster of Paris is more affordable and widely accessible, making it the go-to option in many clinics and hospitals, especially in resource-limited settings.

H. Environmental Impact: Think Green

With growing awareness about environmental impact:

Fiberglass, being a synthetic material, is less eco-friendly and can pose disposal challenges.
Plaster of Paris is derived from natural materials and is more environmentally friendly, though proper disposal is still necessary.

I. Clinical Applications: The Right Cast for the Right Case

Fiberglass is often recommended for long-term use and in cases where the patient is likely to remain active.
Plaster of Paris is ideal for short-term immobilization or initial treatments, particularly when budget constraints are a concern.

Making the Right Choice : Choosing between Fiberglass and Plaster of Paris bandages depends on several factors, including the patient’s lifestyle, the duration of immobilization, and budget.

Fiberglass is generally favoured for its durability and water resistance, while Plaster of Paris remains a trusted option for initial and short-term care due to its affordability and ease of use.

For more insights and to explore our range of orthopaedic casting products, visit our website: Velcast™ – Orthopaedic Fiberglass Casting Tape, Osteopop™ – Plaster of Paris Bandage and Velpop® – Plaster of Paris Bandage. Discover the best solutions for your orthopaedic needs today!

US Patent Granted for a Novel Herbal Dressing

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