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Depression More than a Brain Chemical Imbalance
Depression More than a Brain Chemical Imbalance

When you are feeling sad for a prolonged period of time and you can’t find any specific reason for it, you might be in the clutches of depression and need to seek professional help. Depression is a common and a widely observed mental disorder which affects people of all ages.

As per WHO, more than 300 million people worldwide suffer from depression. You may not know that the person sitting next to you and laughing with you might be under the tight grip of depression.

People often feel reluctant to seek help. Therefore, it is a highly underdiagnosed and untreated problem. Let’s understand what depression is and how we can help our near ones suffering from depression.

Depression Defined:
Depression or major depressive disorder is a serious mood disorder accompanied by a never-ending sadness or loss of interest. Depression can lead to a variety of physical and emotional problems. These problems may affect how a person feels and behaves towards day-to-day activities. However, for a person to be diagnosed with depression, the symptoms must last for at least 2 weeks.

The symptoms of depression in adults differ from person to person, as no two people are affected the same way.

  1. Symptoms in children may include sadness, irritability, pain, clinginess, worry, refusing to go to school, or being underweight.
  2. Teenage symptoms of depression may include being sad, irritability, extremely sensitive, feeling negative, worthless & misunderstood, anger, poor performance at school, addiction to drugs or alcohol, self-harm, too much eating or sleeping, losing interest in normal activities, and avoiding social interaction.
  3. Symptoms in Adults may include the following:
    • Memory difficulties
    • Personality changes
    • Physical aches, Fatigue, loss of appetite, sleep problems or loss of interest in sex — not caused by any other medical condition or medications
    • Feeling excluded or dissociated
    • Suicidal thinking or feelings

Prolonged depression is one of the leading causes of suicide. What makes it dangerous is the fact that those who are suffering from depression are unpredictable.

As per WHO, nearly 8 lac people commit suicide every year making it the second leading cause of deaths among people aged 15-29 years.

What causes depression:
1. Brain Chemistry: Our brain uses chemical messengers called neurotransmitters to communicate with its other parts or nervous system. Any problem or imbalances in the brain related to neurotransmitters have been linked to depression. For example, a decrease in the production of some specific neurotransmitters like serotonin, dopamine & norepinephrine (noradrenaline) by the neurons is responsible for creating a depressed mood and stress.

2. Hormones imbalance: An imbalance in hormonal levels may trigger depression. For example, post-partum depression (peripartum depression) or depression resulting from thyroid problems, menopause (premenstrual dysphoric disorder) or other conditions.

3. Inherited traits: People with family history of depression are more likely to suffer from depression. Research is going on to find depression causing genes.

4. Biological differences & Personality: People who had faced depression prior in their lives appear to have some physical changes in their brains triggering the risk of being depressed. Pessimists and people with low self-esteem are also more likely to experience depression.

5. Environmental factors: An exposure to violence, stress, trauma, major life changes, abuses, poverty, neglect, rejection may increase the chances of depression.

Yes, it is treatable!

Depression is different for all those who are affected by it. There is no “one-size-fits-all” treatment method. It may take a while for the doctor to understand the symptoms and define the treatment methods. The sooner the treatment begins, the more effective it is.

Medications: Anti-depressants are effective for moderate to severe depression cases. The ultimate aim is to improve the brain’s ability to regulate mood. Antidepressants work by increasing the concentration of neurotransmitters in the synapse (space between two nerve cells or neurons through which information is passed from one neuron to another). These are selective serotonin reuptake inhibitors [SSRIs] and must not be considered as the first line of treatment for mild depression cases, and children.

Psychotherapies: Psychotherapies are also called “Talk Therapy” or “Counselling”. Several types of counselling techniques are available which could help the patients. For example, Behavioural Activation, Cognitive Behavioural Therapy [CBT], Problem Solving Therapy and Interpersonal Psychotherapy [IPT].

Brain Stimulation Therapies: Brain Stimulation Therapies like electroconvulsive therapy (ECT) work better in patients with severe depression where other treatment methods fail to work. ECT is also a good treatment option for pregnant women where medications might harm the foetus or in old age patients who can’t tolerate drug side effects. Other treatment modalities used to treat medication-resistant depression include repetitive transcranial magnetic stimulation (rTMS) and vagus nerve stimulation (VNS).

Beyond treatment:

Things we can do to support someone who’s depressed

- Be patient
- Be on their side: Convey a sense of understanding.
- Be Sympathetic: Avoid pointing out and accusatory tones.
- Offer to help
- Don’t criticize or judge or compare 

Depression shouldn’t be ignored for long. Measures need to be taken as soon as possible so as to avoid any unpleasant happening. Never leave a depressed person alone. Speaking one’s heart out can help to ease the burden to a great extent. Apart from that, see a doctor immediately.

Visit www.dattmedi.com for more infomation.
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Velfour® is a revolutionary 4-layer compression bandaging system designed to manage venous leg ulcers and associated conditions. With a sub-bandage pressure of 35-40 mm Hg at the ankle, this high-compression system incorporates elastic layers to achieve sustained compression and promote healing.

Velfour® consists of four essential components that work together synergistically to deliver effective compression and support:

1. Velfour®#1 (Orthopaedic wool):

This layer serves as the primary absorbent material, effectively managing exudate while redistributing pressure evenly around the limb.

2. Velfour® #2 (Cotton crepe bandage):

Designed to enhance absorbency, the cotton crepe bandage smooths out the Orthopaedic Wool layer, ensuring optimal comfort and performance.

3. Velfour®#3 (Elastic Compression Bandage):

The first layer of elastic compression sub-bandage, exerting a pressure of approximately 17 mm Hg at the ankle. This layer provides the initial compression necessary for effective treatment.

4. Velfour® #4 (Cohesive Bandage):

The second layer of compression, adding the remaining 23 mm Hg of pressure while ensuring the bandage remains securely in place. The cohesive properties of this bandage contribute to its stability and adherence.

Velfour® offers a range of features and benefits that make it an exceptional choice for venous leg ulcer management:

1. Effective compression:

With a pressure of approximately 40 mm Hg at the ankle, it delivers the necessary compression to promote healing, gradually reducing to 17 mm Hg at the knee. This graduated compression approach ensures optimal therapeutic results.

2. Graduated compression:

The bandage provides high compression at the ankle and gradually decreases the pressure at the calf.

3. Sustained compression:

It maintains a consistent level of compression for up to a full week, allowing for uninterrupted therapy and reducing the frequency of bandage changes. The treatment process is made simpler by this feature, which also increases patient compliance.

The leading option for treating venous leg ulcers, Velfour® also has additional advantages for a number of other ailments, such as:

1. Treatment of Venous Ulcers:

It improves results by hastening the healing process and facilitating the closure of venous leg ulcers.

2. Prevention of Ulcer Recurrence:

In cases where traditional compression stockings are not tolerated, It provides an effective alternative for preventing the recurrence of venous ulcers.

3. Symptomatic Relief of Superficial Thrombophlebitis:

The compression offered by Velfour®alleviates pain and inflammation associated with superficial thrombophlebitis, providing much-needed comfort to patients.

4. Traumatic Wounds with Local Edema:

It aids in reducing edema and promoting the healing of traumatic wounds, helping to restore the affected area to its optimal state.

5. Venous/Lymphatic Disorders:

It is suitable for managing various venous and lymphatic disorders by providing effective compression and support.

To ensure the optimal application and use of Velfour®, it is essential to follow these guidelines:

1. Limb Assessment:

Accurate measurement of the ankle circumference is crucial to determine the appropriate combination of bandages needed. Any changes in limb contour should also be noted for reference.

2. Wound Assessment:

Mapping the ulcer provides a baseline to track progress throughout the treatment. Regular wound assessment enables healthcare professionals to evaluate the effectiveness of Velfour® and make necessary adjustments.

3. Pain Assessment:

This plays a crucial role in managing venous leg ulcers. Compression therapy with it can alleviate pain, although a slight increase may occur initially.

Velfour® stands as a game-changing solution for managing venous leg ulcers. Its innovative 4-layer compression bandage system, combined with its effective pressure distribution and sustained compression, offers unparalleled benefits for patients and healthcare professionals alike.

We are committed to providing valuable information and insights to support your journey towards improved wound healing and patient well-being.

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