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Depression More than a Brain Chemical Imbalance
Depression More than a Brain Chemical Imbalance

When you are feeling sad for a prolonged period of time and you can’t find any specific reason for it, you might be in the clutches of depression and need to seek professional help. Depression is a common and a widely observed mental disorder which affects people of all ages.

As per WHO, more than 300 million people worldwide suffer from depression. You may not know that the person sitting next to you and laughing with you might be under the tight grip of depression.

People often feel reluctant to seek help. Therefore, it is a highly underdiagnosed and untreated problem. Let’s understand what depression is and how we can help our near ones suffering from depression.

Depression Defined:
Depression or major depressive disorder is a serious mood disorder accompanied by a never-ending sadness or loss of interest. Depression can lead to a variety of physical and emotional problems. These problems may affect how a person feels and behaves towards day-to-day activities. However, for a person to be diagnosed with depression, the symptoms must last for at least 2 weeks.

The symptoms of depression in adults differ from person to person, as no two people are affected the same way.

  1. Symptoms in children may include sadness, irritability, pain, clinginess, worry, refusing to go to school, or being underweight.
  2. Teenage symptoms of depression may include being sad, irritability, extremely sensitive, feeling negative, worthless & misunderstood, anger, poor performance at school, addiction to drugs or alcohol, self-harm, too much eating or sleeping, losing interest in normal activities, and avoiding social interaction.
  3. Symptoms in Adults may include the following:
    • Memory difficulties
    • Personality changes
    • Physical aches, Fatigue, loss of appetite, sleep problems or loss of interest in sex — not caused by any other medical condition or medications
    • Feeling excluded or dissociated
    • Suicidal thinking or feelings

Prolonged depression is one of the leading causes of suicide. What makes it dangerous is the fact that those who are suffering from depression are unpredictable.

As per WHO, nearly 8 lac people commit suicide every year making it the second leading cause of deaths among people aged 15-29 years.

What causes depression:
1. Brain Chemistry: Our brain uses chemical messengers called neurotransmitters to communicate with its other parts or nervous system. Any problem or imbalances in the brain related to neurotransmitters have been linked to depression. For example, a decrease in the production of some specific neurotransmitters like serotonin, dopamine & norepinephrine (noradrenaline) by the neurons is responsible for creating a depressed mood and stress.

2. Hormones imbalance: An imbalance in hormonal levels may trigger depression. For example, post-partum depression (peripartum depression) or depression resulting from thyroid problems, menopause (premenstrual dysphoric disorder) or other conditions.

3. Inherited traits: People with family history of depression are more likely to suffer from depression. Research is going on to find depression causing genes.

4. Biological differences & Personality: People who had faced depression prior in their lives appear to have some physical changes in their brains triggering the risk of being depressed. Pessimists and people with low self-esteem are also more likely to experience depression.

5. Environmental factors: An exposure to violence, stress, trauma, major life changes, abuses, poverty, neglect, rejection may increase the chances of depression.

Yes, it is treatable!

Depression is different for all those who are affected by it. There is no “one-size-fits-all” treatment method. It may take a while for the doctor to understand the symptoms and define the treatment methods. The sooner the treatment begins, the more effective it is.

Medications: Anti-depressants are effective for moderate to severe depression cases. The ultimate aim is to improve the brain’s ability to regulate mood. Antidepressants work by increasing the concentration of neurotransmitters in the synapse (space between two nerve cells or neurons through which information is passed from one neuron to another). These are selective serotonin reuptake inhibitors [SSRIs] and must not be considered as the first line of treatment for mild depression cases, and children.

Psychotherapies: Psychotherapies are also called “Talk Therapy” or “Counselling”. Several types of counselling techniques are available which could help the patients. For example, Behavioural Activation, Cognitive Behavioural Therapy [CBT], Problem Solving Therapy and Interpersonal Psychotherapy [IPT].

Brain Stimulation Therapies: Brain Stimulation Therapies like electroconvulsive therapy (ECT) work better in patients with severe depression where other treatment methods fail to work. ECT is also a good treatment option for pregnant women where medications might harm the foetus or in old age patients who can’t tolerate drug side effects. Other treatment modalities used to treat medication-resistant depression include repetitive transcranial magnetic stimulation (rTMS) and vagus nerve stimulation (VNS).

Beyond treatment:

Things we can do to support someone who’s depressed

- Be patient
- Be on their side: Convey a sense of understanding.
- Be Sympathetic: Avoid pointing out and accusatory tones.
- Offer to help
- Don’t criticize or judge or compare 

Depression shouldn’t be ignored for long. Measures need to be taken as soon as possible so as to avoid any unpleasant happening. Never leave a depressed person alone. Speaking one’s heart out can help to ease the burden to a great extent. Apart from that, see a doctor immediately.

Visit www.dattmedi.com for more infomation.
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Allergies are a common health issue that affect a significant portion of the population worldwide. Allergies are a hypersensitive reaction of the immune system to an otherwise harmless substance, which is known as an allergen. The allergen can be any substance that triggers an allergic reaction in the body, such as pollen, dust, food, or animal dander.

Allergies are caused due to the abnormal response of the immune system, which mistakes a harmless substance for a harmful invader and initiates a defence mechanism, called antibodies, to protect the body from it. This results in various allergic reactions, such as skin rashes, itching, sneezing, watery eyes, and in severe cases, anaphylaxis.

There are various reasons behind the occurrence of allergies. Genetics plays a significant role in determining an individual’s likelihood of developing allergies. Environmental factors such as exposure to pollution, chemicals, and toxins can also trigger allergies.

There are several different types of allergies, each with their unique symptoms and triggers.

Some of the most common types of allergies include:

1. Respiratory allergies:

These allergies are triggered by airborne allergens such as pollen, dust mites, and animal dander. The symptoms of respiratory allergies include sneezing, coughing, and wheezing.

2. Food allergies:

These allergies occur when the immune system reacts to certain foods, such as nuts, shellfish, and eggs. Symptoms of food allergies can range from mild itching, tingling in the mouth, hives, swelling of the lips, tongue, face or throat to more severe life-threatening anaphylaxis.

3. Skin allergies:

These allergies occur when the skin comes into contact with an allergen, such as certain fabrics, metals, or cosmetics. The symptoms of skin allergies include rashes, itching, and swelling.

4. Insect allergies:

These allergies occur when an individual is bitten or stung by an insect, such as bees or mosquitoes. The symptoms of insect allergies can range from mild itching to severe anaphylaxis.

5. Medicine allergies:

Medicine allergies are hypersensitive reactions of the immune system to certain medications. They can cause symptoms like skin rashes, itching, swelling, and in severe cases, difficulty breathing or anaphylaxis. It is important to communicate medicine allergies to healthcare providers to ensure safe and effective treatment.

Precautionary methods can be taken to manage allergies. Firstly, it is crucial to identify the allergen that triggers the allergic reaction. This can be done through various tests such as skin tests or blood tests. Once the allergen is identified, it is essential to avoid exposure to it. For example, individuals with food allergies must avoid eating the allergen-containing food.

Similarly, those with respiratory allergies must avoid exposure to airborne allergens, such as pollen or animal dander. If a person has a known severe allergy then they can also wear a medical alert bracelet, which lets others know that you have a serious allergy incase they are unable to communicate it.

Medications such as antihistamines, decongestants, and corticosteroids can be used to manage allergy symptoms. In severe cases, epinephrine injections may be required to manage anaphylaxis.

In addition to medication, several lifestyle changes can also help manage allergies. One of the most important being to try to reduce stress levels. While stress can’t trigger an allergic reaction it can make it worse if you are having one. When in stress your body releases hormones including histamine, which is a powerful chemical that leads to allergy symptoms thus making the reaction worse.

Allergies can significantly impact the lives of those who suffer from them. However, with proper management, it is possible to reduce the severity of allergy symptoms. If you suspect that you have an allergy, it is important to seek medical advice and get a proper diagnosis.

We advice to follow precautionary methods and working with a healthcare professional, that can help you manage allergies and improve your quality of life. Follow us for more such information.

Intravenous (IV) cannulation is a common medical procedure used to administer medications and fluids directly into the bloodstream. While the benefits of IV therapy are clear, the procedure also poses risks, including the possibility of infection at the site of cannula insertion. When it comes to IV therapy, securing the cannula in place is critical for the patient’s safety and comfort.

We present Velfix® -Edge, a specialized IV dressing designed specifically for fixing cannulas, which is used to reduce the associated risks. Velfix® -Edge is a non-woven bordered IV dressings coated with latex free adhesive. Frame delivery system for precise placement. Highly conformable to provide solutions for difficult catheters and IV sites. Promotes best practice and enhanced patient comfort with additional securement strips and date labels. Window Framed delivery system allows for one handed application and prevents dressing sticking to itself. Deep notched design forms a barrier to secondary infection and bacterial contamination.

Some of the unique features and benefits of Velfix® -Edge:

  • It has a window frame design that enables continuous observation of the IV site, which is important for monitoring the patient’s condition and detecting any potential complications.
  • It offers a waterproof sterile barrier that protects the site from external contaminants, reducing the risk of infection.
  • It has stabilization non-woven borders that ensure maximum securement, breathability, and wear time.
  • Its notched design helps to discourage edge lift, which could compromise the sterile environment of the site.
  • It comes with two securement tape strips and a pre-printed documentation label, which facilitates proper labelling and documentation of the procedure.
  • It is easy to handle with gloves and allows for single-handed application, which saves time and improves efficiency.

There are several IV dressings available in the market but Velfix® -Edge stands out from the competition and enables medical practitioners to easily monitor the cannula insertion site.

Instructions for Use:

Velfix® -Edge must be used correctly in order to be effective. Before applying the dressing, the skin in the area of the cannula insertion site needs to be properly washed and dried. The Velfix® -Edge dressing can be placed directly to the skin once the region has been cleaned and dried, ensuring that the cannula stays firmly in place. As directed, the dressing should be changed often.

Precautions and Warnings:

The use of Velfix® -Edge on wounds or other skin-compromised areas is not recommended. It ought to be used exclusively for cannula fixation. Additionally, patients should not use Velfix® -Edge if they have allergies to adhesives or other substances.

Also, to maintain its efficacy and safety, it is crucial to carefully follow the usage instructions and adopt the appropriate safety measures. For securing cannulas, Velfix® -Edge is a great choice and is available in a range of tailored sizes.

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